Promiscuity appeals to chemical engineers, under certain circumstances. One set of those circumstances is described in the paper: “Engineering Sialidase Specificity: Taking Advantage of the Promiscuous One,” J.N. Watson, A.J. Bennet, presented at the 23rd International Carboyhdrate Symposium, held in Whistler, BC, Canada, July 23-28, 2006. The authors are at Simon Fraser University, Burnaby, Canada.