The man who invented the printing press planned to make good, practical use of it, according to Michael Lewis (writing in Vanity Fair):
The first thing Gutenberg [pictured here] sought to publish, after the Bible, was a laxative timetable he called a “Purgation-Calendar.”
Here is a fragment of that Purgation-Calendar (reprinted in An introduction to the history of medicine, with medical chronology, bibliographic data and test questions, by Fielding Hudson Garrison, W.B. Saunders Company, 1913.):
(Thanks to investigator Mark Dionne for bringing this to our attention.)