New meds are best, or maybe not

neuroleptics.jpgPerverse incentives in drug development, research, marketing and clinical usage can be illustrated by considering the example of the so- called ?atypical? neuroleptics which have grown to become a standard ? indeed expanding - part of psychiatric practice despite their probable inferiority to older sedative agents. There is now ample evidence to suggest that neuroleptics (aka. anti-psychotics and major tranquillizers) are dangerous drugs, and patients? exposure to them should be minimized wherever possible.

so says the study “If ?atypical? neuroleptics did not exist, it wouldn?t be necessary to invent them: perverse incentives in drug development, research, marketing and clinical practice,” Bruce G. Charlton, Medical Hypotheses, vol. 6, 2005, pp. 1005-9. The author is at the University of Newcastle upon Tyne.