Should patients — after they have had poison injected into their face — then squeeze their face? If so, then how often, and exactly where? Those are the bundled questions this study tried to get at, with perhaps a hint that further attempts to answer the questions might be able to produce some hint of possible success of some kind:
“Twelve patients underwent the non-squeeze / squeeze / non-squeeze protocol and the remaining 14 patients underwent the squeeze / non-squeeze / squeeze protocol. All patients experienced at least one treatment with and one treatment without performing post-treatment squeezing exercises….
“Although this study failed to demonstrate an enhanced effect of botulinum toxin-A with muscle contracture in a clinical setting, further studies looking at a more defined subset and larger number of patients could possibly lead to statistical significance.”
The authors also remark: “Although there is a theoretical risk of inadvertent spread of botulinum toxin-A with extensive muscle contraction, no such cases were demonstrated here.”