“The formulation containing the carrier size ranges of 30-71 μm provided the greatest percent FPF [Fine Particle Fraction].
When considering the device resistance, it was found that the tobacco pipes provided a higher device resistance than the Inhalator®.”
Thus the team recommend further research to optimise the pipes :
“[…] they still need some modification to the mouthpiece part by increasing the diameter of the pipes outlet to reduce the drug loss via inertial impaction and decrease the device resistance for ease of inhalation.”
See:’Feasibility studies of using a tobacco pipe as a dry powder inhaler device’ Thai J. Pharm. Sci. 36 (2012) 1-1.
Note: Yes, Improbable did think of titling this article “Ceci n’est pas un inhalateur pour l’asthme” but resisted the temptation.